What if the secret of health lies at the center of disease?
At Sonata, we are designing Network Medicines that reprogram diseased cells to become the coordinators of cure.
About Sonata
Sonata asks the question, what if we could create therapeutics that reprogram diseased cells to become the coordinators of cure?
At Sonata, we believe that the intrinsic hardware diseased cells use to influence their multicellular networks can be reprogrammed to drive robust, durable, and comprehensive cures for a broad range of diseases.
Through a combination of our proprietary genetic library, comprehensive biochemical and functional characterization, and the latest advancements in machine learning algorithms, we are generating a deep understanding of how to reshape multicellular networks to guide the development of transformative therapeutics. While initially focused on oncology, our network-based approach is applicable across many intractable diseases.
Our Science
The Big Data multicellular network problem.
To transform diseased cells into coordinators of cure, you need to holistically understand the multicellular networks in which they are operating.
Cells may be the ultimate Big Data processors, constantly analyzing and responding to a wide variety of signals—from their environment and other cells—that influence their behavior.
Diseased cells often subvert this hardware to send pathologic signals to other cells in their network, perpetuating a cycle of dysfunction and disease progression.
We are redefining the drug development paradigm by designing Network Medicines that reprogram diseased cells to instead release curative signals, resulting in durable disease resolution.
Our Platform
Know, Don’t Guess™
Sonata’s platform delivers unprecedented insights into complex diseases to generate better, earlier decision making during the drug development process and yield more effective treatments across a broad range of diseases.
We maximize the power of machine learning by generating high-throughput datasets of proprietary experimental results upfront, prior to target or therapeutic selection, to know precisely (instead of guessing) what signals are required to drive multicellular networks toward cure and how to stimulate their release.
We use these unique insights to then precision engineer small molecule and genetic-based therapeutics that drive cure.
Our Leadership
Backed by decades of successful drug discovery, drug development and value creation experience, our team leads with a passion and sense of urgency to rapidly bring our innovative therapeutics to patients in need.
Board of Directors
Scientific Advisors & Collaborators
News
Work at Sonata
At Sonata, we are a dynamic, collaborative, and enthusiastic team dedicated to developing drugs that will have significant patient impact. We are looking for individuals with a passion for paradigm-changing ideas to join us.
Contact us
Interested in learning more? We’d love to hear from you.