What if the secret of health lies at the center of disease?
Sonata asks the question, what if we could create therapeutics that reprogram diseased cells to become the coordinators of cure?
Sonata Therapeutics is transforming the drivers of disease to become the coordinators of cure, creating a new class of therapeutics called Network Medicines™. These are the first therapeutics designed specifically to reprogram diseased cells to release signals that modulate and coordinate multicellular networks towards cure. This paradigm shift in drug development – identifying and drugging targets based on their ability to initiate a cascade of activity that optimizes the network effects in the entire disease microenvironment – could significantly advance the field of oncology, fibrosis and many other diseases where multicellular networks play a role in disease initiation and progression.
The Big Data multicellular network problem.
To transform diseased cells into coordinators of cure, you need to holistically understand the multicellular networks in which they are operating.
Cells may be the ultimate Big Data processors, constantly analyzing and responding to a wide variety of signals—from their environment and other cells—that influence their behavior.
Diseased cells often subvert this hardware to send pathologic signals to other cells in their network, perpetuating a cycle of dysfunction and disease progression.
We are redefining the drug development paradigm by designing Network Medicines™ that reprogram diseased cells to instead release curative signals, resulting in durable disease resolution.
Know, Don’t Guess™
Sonata’s platform delivers unprecedented insights into complex diseases to generate better, earlier decision making during the drug development process and yield more effective treatments across a broad range of diseases.
We maximize the power of machine learning by generating high-throughput datasets of proprietary experimental results upfront, prior to target or therapeutic selection, to know precisely (instead of guessing) what signals are required to drive multicellular networks toward cure and how to stimulate their release.
We use these unique insights to then precision engineer small molecule and genetic-based therapeutics that drive cure.
Backed by decades of successful drug discovery, drug development and value creation experience, our team leads with a passion and sense of urgency to rapidly bring our innovative therapeutics to patients in need.
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Work at Sonata
At Sonata, we are a dynamic, collaborative, and enthusiastic team dedicated to developing drugs that will have significant patient impact. We are looking for individuals with a passion for paradigm-changing ideas to join us.
Interested in learning more? We’d love to hear from you.